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Oral chemotherapy is associated with many advantages, including ease of use and convenience for patients, a reduction in both time and costs associated with traveling to hospitals for IV chemotherapy infusions, and possible improvements in the quality of life of patients taking oral chemotherapy (as opposed to IV formulations). Hosp Pharm Eur. This change was made as a result of many studies that were conducted and revealed a need for a CSTD. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. While cancer cells are these kinds of cells, other cells in your body divide quickly as well. Oral chemotherapy agents should never be placed in an automated dispensing machine or robot as this can compromise the integrity of the medication by accidentally crushing or cutting the dose. Chemotherapeutic agents, regardless of formulation, are medications with NTIs. The same handwashing procedures used with IV chemotherapy should be followed (i.e., wash hands before putting on and after taking off the gloves). J Occup Environ Med. The Pharmacist's Role in Testicular Cancer Treatment, Drug Combination Slows Prostate Cancer Growth, Exhaled Breath May Signal Early Lung Cancer, Regular NSAID Use by Type 1 Endometrial Cancer Patients Linked to Mortality. Handling of oral chemotherapy can affect all types of pharmacies, whether retail, hospital, or specialty, and even a physicians office. 4. 2143 0 obj <> endobj The outcome of this study showed that facilities should maintain proper clean rooms, pass-through hatches, and personal protective equipment, and should utilize CSTDs.5. This has been an ongoing concern for years in the healthcare industry. 45---pinch an inch 90-----pinch two inches. J Oncol Pract. Pharm Purchasing Prod. Table 7 in Chemotherapy and Biotherapy Guidelines and Recommendations for Practice discusses special features required for administration, but package inserts should be referred to for the most up-to-date information. 1. If you continue browsing the site, you agree to the use of cookies on this website. Because many chemotherapy regimens employ the use of oral agents, it is essential that patients, caretakers, and healthcare providers be educated on how to safely handle these medications to optimize therapy for the patient and reduce risk to all others who come into contact with these drugs.8-10. 2013 updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy admin-istration safety standards including standards for the safe administration and management of oral chemotherapy. 2010;52(10):1019-1027. PREPARING CHEMOTHERAPEUTIC DRUGS ORGANIZING DRUG PREPARATION AREAS (cont.) In a March 2011 editorial in the Journal of Oncology Pharmacy Practice, the authors concluded that if the different closed systems currently available are equally effective, then the choice comes down to cost and ease of use.13 CSTDs are an annual expense, but the expense is outweighed by the ethical responsibility to protect the employees. Accessed July 2, 2014. Use the medication administration steps outlined earlier then.. Usually mark site with indeliable pen for easy identification for reading of allergy or PPD test. If you wish to opt out, please close your SlideShare account. Exposure to hazardous drugs in healthcare: an issue that will not go away. I can recommend a site that has helped me. One study funded by NIOSH looked at pharmacy and nursing personnel to provide more evidence for the risks healthcare workers face when preparing, administering, dispensing, and/or transporting chemotherapy.5 One of the purposes of the study was to investigate specific chromosomal changes that occur in healthcare workers and their level of the exposure. Illinois Council of Health-Systems Pharmacists Spring Meeting; March 9, 2012. http://bit.ly/1xi6QR4. Chemotherapy The aim of chemotherapy is to do the maximum damage to cancer cells while causing the minimum damage to healthy tissue. It is the use of cytotoxic drugs to destroy cancer cells Chemotherapy affects the entire body. 3 Chemotherapy Cytotoxic drugs (antineoplastic, anticancer or cancer chemotherapy drugs) include a wide range of chemical compounds. Irene Weru 2011;17(1):9-13.14. Drug Distribution and Control: Preparation and HandlingGuidelines. J Oncol Pharm Pract. If youre struggling with your assignments like me, check out www.HelpWriting.net . When oral chemotherapy agents are stored, they should have their own designated area in the pharmacy, and special instructions should be followed if necessary (e.g., protect from light).8 Some of the risks of exposure to oral chemotherapy for healthcare workers depend on the formulation of the medication (i.e., uncoated vs. coated tablets). Pharm Pract News. 13. Chemotherapy agents often have a narrow therapeutic index (NTI) and are frequently given in combination, which increases adverse effects and exposure risks.7,8 Some of these effects can be minor, such as headache, dizziness, mucosal sores, contact dermatitis, minor hair loss, and tissue injury; but others can be more severe and long-term, such as infertility, miscarriage, leukemia, and congenital malformations.8. If you continue browsing the site, you agree to the use of cookies on this website. You can change your ad preferences anytime. 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