September 3, 2020

maybe not colleen hoover summary

by Admin

for the cost-effective production of high-value pharmaceuticals in the blood or milk of transgenic sheep or cows. The first transgenic cow was produced in 1997. Uses of modified milk From: Mucosal Immunology (Fourth Edition), 2015 In June 2006, the first therapeutic protein made in a transgenic animal was approved for use in Europe and the USA. Transgenic animals can be engineered to do a number of different things for economic purposes. Pigs could be engineered to put on more muscle mass so that more food can be produced. This is because the casein micelles in the milk are smaller, which affects the milk’s light scattering properties. The milk from transgenic cows and goats contains these human proteins. The rhLf-transgenic cows showed milder systemic signs and lower serum cortisol and haptoglobin concentrations than did controls. This milk can protect consumers against bacterial infections (Brundige, Maga, Klasing, & Murray, 2009 ; Yang et al., 2009 ). Transgenic cattle have been generated by transferring a human artificial chromosome vector carrying the entire unrearranged, human Ig heavy (hIGH) and κ-light (hIGK) chain loci to bovine fibroblasts in which two endogenous bovine IgH chain loci were inactivated (Kuroiwa et al., 2009). Animals can even be engineered to mature more quickly so that they can become more profitable for the modern farmer. All cows became infected and developed clinical mastitis. It is a relatively new technology, but several transgenic breeds have since been developed. Transgenic cows can be used as ‘biofactories’ to produce human therapeutic proteins (proteins that are used to treat diseases). The milk from casein transgenic cows contained double the levels of kappa casein than milk from control cows. The high Lf concentrations in the milk of transgenic cows did not protect them from intramammary infection. Milk may therefore also be the carrier of other proteins, namely of monoclonal antibodies having anti-pathogen activities. Cattle produced by cloning methods tend to have longer gestation periods and higher birth weights, resulting in a higher rate of Caesarean births (NRC, 2002; AEBC, 2002). In biotechnology, the use of large transgenic animals or ‘bioreactors’ has been attempted, e.g. Another promising area for the exploitation of the transgenic technology has been in the field of xenotransplantation, where transgenic pigs are engineered to express immunological characteristics … Cows are an attractive target for transgenesis because they naturally secrete large quantities of protein in their milk. This means that, if done correctly, the protein encoded by a transgene will be expressed in the cows milk and can easily be isolated. 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