September 3, 2020

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The alleles B*1501, *1504, *1507, *1527, *1530, *1532, *1535, * 1538, and *1545 have been defined in the HLA “Dictionary” (2) as B62. These are a few matching rules: Be The Match® requires that patients and donors from the Be The Match Registry® match at least 6 of 8 HLA markers. Research shows that cells from younger donors lead to more successful transplants. By far, the most common reason for HLA typing is to help determine which people can provide the safest tissue transplants (solid organ or hematopoietic stem cell transplantation).1 Potential tissue recipients must have the typing, as must anyone who might potentially want to donate tissue. People can also volunteer to have their HLA type included in a bone marro… Research shows that patients have better outcomes (results) with a closely matched donor. Transplant research, clinical studies, publications and outcomes data for researchers and clinicians. Your immune system uses these markers to recognize which cells belong in your body and which do not. Identify, decode, or expand a specific MAC (NMDP allele code), which may be used when reporting HLA typing results or when evaluating allele combinations. Request HLA Today Kits How HLA Today Works Follow us on Facebook to stay up to date with all Be The Match stories and events. This site requires JavaScript How to enable JavaScript. URD who were a potential match for a PP by low/intermediate resolution were HLA typed by sequence-based typing to resolve the matching status. Proven solutions for organizations developing and delivering new cellular therapies. Human leukocyte antigen (HLA) typing is used to match patients and donors for bone marrow or cord blood transplants. The 8/8 match rate for WH PP improved from 68% in 2009 to 72% in 2012. MAC published list List of alleles up through the most recent version of the IMGT HLA Database. NMDP and CIBMTR HLA Matching Guidelines The remaining (rare) alleles type as B15, are null, or are undefined. Bill Young Cell Transplantation Program. IPD-IMGT/HLA The degree of human leukocyte antigen (HLA) matching between the transplant recipient and the hematopoietic cell graft has a significant impact the outcomes of related and unrelated donor hematopoietic cell transplantation (HCT). Doctors choose donors based on what is best for their patient. Be The Match Official Facebook. This might include relatives of someone needing a transplant. Through the HLA Today initiative, the National Marrow Donor Program® (NMDP)/Be The Match® is providing high resolution human leukocyte antigen (HLA) typing and a preliminary donor search report for patients newly diagnosed with blood cancers and disorders at no charge to providers or patients. Email Print This Page When more than one potential donor is a good HLA match for a patient, doctors will also consider other factors, including the donor’s age. High-Resolution HLA Alleles and Haplotypes in the US Population, Jewish High-Resolution Haplotype Frequencies, Be The Match Registry Haplotype Frequencies, Allele Code Update to Version 3 WHO Nomenclature, MAC Service UI (NMDP allele code creation), C.W. HLA are proteins -- or markers -- found on most cells in your body. Information and support for patients, donors and supporters of our mission. You are using an outdated browser. Please upgrade your browser to improve your experience. Corresponding match rates were 41% to 44% for HIS, 44% to 46% for API, and 27% to 30% for AFA, for 2009 and 2012, respectively. Sometimes doctors want to match 8 HLA markers. Javascript disabled. Match result: B62 would be a “zero mismatch” for B62 recipients only. Other times, doctors want to match 10 markers. 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