otwlpCUbyN5kTf9k,n%"/+"VrKF]~/*>!Zk\J[ Carcinogenesis 5: 875878, 1984, Dontenwill W: Experimental studies on the organotropic effect of nitrosamines in the respiratory tract. Cancer Letters 10: 32531, 1980, Rao MS, Scarpelli DG, Lijinsky W: Carcinogenesis in Syrian hamsters by N-nitroso-2,6-dimethylmorpholine, its cis and trans isomers, and the effect of deuterium labeling. Tetrahedron 37: 41434149 1981, Love LA, Lijinsky W, Keefer LK, Garcia H: Chronic oral administration of 1-nitrosopiperazine at high doses to MRC rats. Carcinogenesis 6: 641643, 1985, Goth R, Rajewsky MF: Persistence of O6-ethylguanine in rat brain DNA. Synthesis, X-ray crystallography, and N-N rotational barrier. 57, Lyon. Cancer Res 42: 5458, 1982, Lijinsky W: Metabolism and cellular interactions of some aliphatic nitrogenous carcinogens. Biochem J 212: 599608, 1983, Farrelly JG, Thomas BJ, Lijinsky W: Metabolism and cellular interactions of N-nitrosodiethanolamine. Carcinogenesis 1: 157160. 112: 229239, 1986, Lijinsky W, Reuber MD: Carcinogenicity of deuteriumlabeled N-nitroso-N-methyleyclohexylamine in rats. Cancer Lett 8: 2934, 1979. Clipboard, Search History, and several other advanced features are temporarily unavailable. Phantom Killer, Lego Jurassic Park Set Rumors, Watch The Sun Live, Is The Good Doctor On Disney, Gorka Suit, Pelican Rest Tourist Park St George Qld St George Qld, Elise Bachelor, Leo Compatibility With Leo, The Good Doctor Season 1 Episode 1 Netflix, China Productivity, "/> otwlpCUbyN5kTf9k,n%"/+"VrKF]~/*>!Zk\J[ Carcinogenesis 5: 875878, 1984, Dontenwill W: Experimental studies on the organotropic effect of nitrosamines in the respiratory tract. Cancer Letters 10: 32531, 1980, Rao MS, Scarpelli DG, Lijinsky W: Carcinogenesis in Syrian hamsters by N-nitroso-2,6-dimethylmorpholine, its cis and trans isomers, and the effect of deuterium labeling. Tetrahedron 37: 41434149 1981, Love LA, Lijinsky W, Keefer LK, Garcia H: Chronic oral administration of 1-nitrosopiperazine at high doses to MRC rats. Carcinogenesis 6: 641643, 1985, Goth R, Rajewsky MF: Persistence of O6-ethylguanine in rat brain DNA. Synthesis, X-ray crystallography, and N-N rotational barrier. 57, Lyon. Cancer Res 42: 5458, 1982, Lijinsky W: Metabolism and cellular interactions of some aliphatic nitrogenous carcinogens. Biochem J 212: 599608, 1983, Farrelly JG, Thomas BJ, Lijinsky W: Metabolism and cellular interactions of N-nitrosodiethanolamine. Carcinogenesis 1: 157160. 112: 229239, 1986, Lijinsky W, Reuber MD: Carcinogenicity of deuteriumlabeled N-nitroso-N-methyleyclohexylamine in rats. Cancer Lett 8: 2934, 1979. Clipboard, Search History, and several other advanced features are temporarily unavailable. Phantom Killer, Lego Jurassic Park Set Rumors, Watch The Sun Live, Is The Good Doctor On Disney, Gorka Suit, Pelican Rest Tourist Park St George Qld St George Qld, Elise Bachelor, Leo Compatibility With Leo, The Good Doctor Season 1 Episode 1 Netflix, China Productivity, " /> otwlpCUbyN5kTf9k,n%"/+"VrKF]~/*>!Zk\J[ Carcinogenesis 5: 875878, 1984, Dontenwill W: Experimental studies on the organotropic effect of nitrosamines in the respiratory tract. Cancer Letters 10: 32531, 1980, Rao MS, Scarpelli DG, Lijinsky W: Carcinogenesis in Syrian hamsters by N-nitroso-2,6-dimethylmorpholine, its cis and trans isomers, and the effect of deuterium labeling. Tetrahedron 37: 41434149 1981, Love LA, Lijinsky W, Keefer LK, Garcia H: Chronic oral administration of 1-nitrosopiperazine at high doses to MRC rats. Carcinogenesis 6: 641643, 1985, Goth R, Rajewsky MF: Persistence of O6-ethylguanine in rat brain DNA. Synthesis, X-ray crystallography, and N-N rotational barrier. 57, Lyon. Cancer Res 42: 5458, 1982, Lijinsky W: Metabolism and cellular interactions of some aliphatic nitrogenous carcinogens. Biochem J 212: 599608, 1983, Farrelly JG, Thomas BJ, Lijinsky W: Metabolism and cellular interactions of N-nitrosodiethanolamine. Carcinogenesis 1: 157160. 112: 229239, 1986, Lijinsky W, Reuber MD: Carcinogenicity of deuteriumlabeled N-nitroso-N-methyleyclohexylamine in rats. Cancer Lett 8: 2934, 1979. Clipboard, Search History, and several other advanced features are temporarily unavailable. Phantom Killer, Lego Jurassic Park Set Rumors, Watch The Sun Live, Is The Good Doctor On Disney, Gorka Suit, Pelican Rest Tourist Park St George Qld St George Qld, Elise Bachelor, Leo Compatibility With Leo, The Good Doctor Season 1 Episode 1 Netflix, China Productivity, " />
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Ecotoxicology and Environ Safety 2: 421426, 1978, Preussmann R, Habs M, Pool B, Stummeyer D, Lijinsky W, Reuber MD: Fluoro-substituted N-nitrosamines. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Cancer Letters 14: 297302. J Am Chem Soc 92: 57475748, 1970. Carcinogenesis 1: 753757, 1980, Lijinsky W, Taylor HW: Carcinogenicity of two unsaturated derivatives of nitrosopiperidine in Sprague-Dawley rats. Learn more about Institutional subscriptions, Barnes JM, Magee PN: Some toxic properties of dimethylnitrosamine. 79 0 obj <>/Filter/FlateDecode/ID[<8865FE7FC7BA4A46AA571DFF7FCD2855>]/Index[60 37]/Info 59 0 R/Length 90/Prev 89576/Root 61 0 R/Size 97/Type/XRef/W[1 2 1]>>stream Carcinogenesis 5: 167170, 1984, Lijinsky W, Knutsen GM, Kovatch RM: Comparative carcinogenesis by hydroxylated nitrosopropylamines in Syrian hamsters. Naturwissenschaften 61: 328, 1974, Lijinsky W: Species differences in nitrosamine carcinogenesis. The effect of N-nitrosohexamethyleneimine in Syrian golden hamsters and Swiss mice. k!~9%.1~FO! Hbd`ab`ddqM,HM,LN Kjg!C,92. Banbury Report 12: Nitrosamines and Human Cancer, Cold Spring Harbor Laboratory. Plenum Publishing Corp, New York, 1984, pp 189231, Lijinsky W, Andrews AW: The mutagenicity of nitrosamides in Salmonella typhimurium. The deficiencies in the mutagenesis assay appear to arise from a lack of the necessary enzymes in the liver microsomal fractions used for activation. This site needs JavaScript to work properly. Subscription will auto renew annually. J Natl Cancer Inst 65: 451453, 1980, Ketkar MD, Mohr U, Lijinsky W: The carcinogenic effect of 1,1-diethyl-3-methyl-3-nitrosourea in Syrian golden hamsters. J Natl Cancer Inst 68: 989991, 1982, Lyle RE, Saavedra JE, Lyle GG, Fribush MM, Marshall JL, Lijinsky W, Singer GM: Conformational stereospecificity in electrophilic reactions with cyclic anions. Z Krebsforsch 90: 227231, 1977, Lijinsky W, Kovatch RM: Carcinogenesis by oxygenated nitrosomethylpropylamines in Syrian hamsters. Cancer Lett 22: 8388, 1984, Lee KY, Lijinsky W, Magee PN: Methylation of ribonucleic acids of liver and other organs in different species treated with C14 and H3-dimethylnitrosamine in vivo. In hamsters, nitrosoalkylureas give rise only to tumors of the forestomach and spleen, but no tumors of the nervous system. hb```f`` While most directly acting N-nitroso compounds and those requiring metabolic activation are mutagenic with appropriate activat - 188.65.220.37. 3. Z Krebsforsch 81: 285310, 1974, Magee PN, Lee KY: Cellular injury and carcinogenesis. 1976;32(3-4):179-228. doi: 10.1016/0165-1110(76)90001-4. Mutagenic and carcinogenic N-nitroso compounds: possible environmental hazards. 0 Evidence for the alkylation of rat liver nucleic acids in vivo by N-nitrosomorpholine. Adv Cancer Res 10: 163246, 1967, Bogovski P, Bogovski S: Animal species in which N-nitroso compounds induce cancer. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo. Some of these are mutagens that are not carcinogenic; others are carcinogens that are nonmutagenic. Cancer Res 35: 21232125. William Lijinsky. Greater effectiveness of hepatocyte and liver S9 preparations from hamsters than rat preparations in activating N-nitroso compounds to metabolites mutagenic to Salmonella. Food Cosmet Toxicol 6: 571, 1968, Lijinsky W, Taylor HW: Carcinogenicity of methylated nitrosopiperidines. Equilibrium constants and protonation site for N-methylbenzenesulfonamides. This implies to directly acting compounds and to those requiring metabolic activation. ]i} .puMmbK|~WA R2Atj(:0_e8)nWE0olFM.[`Qu j%xbLzlT)t;qV9Gc1rnql~dbutbOI$tc~-{&I!)Kmk#,[3.(/EIsi}HNp$IE& '2Mjc_o^wK- -|iVdkkidX+vxSmoslm b,0,dJa6}"wex6LJe qu2`dvT>otwlpCUbyN5kTf9k,n%"/+"VrKF]~/*>!Zk\J[ Carcinogenesis 5: 875878, 1984, Dontenwill W: Experimental studies on the organotropic effect of nitrosamines in the respiratory tract. Cancer Letters 10: 32531, 1980, Rao MS, Scarpelli DG, Lijinsky W: Carcinogenesis in Syrian hamsters by N-nitroso-2,6-dimethylmorpholine, its cis and trans isomers, and the effect of deuterium labeling. Tetrahedron 37: 41434149 1981, Love LA, Lijinsky W, Keefer LK, Garcia H: Chronic oral administration of 1-nitrosopiperazine at high doses to MRC rats. Carcinogenesis 6: 641643, 1985, Goth R, Rajewsky MF: Persistence of O6-ethylguanine in rat brain DNA. Synthesis, X-ray crystallography, and N-N rotational barrier. 57, Lyon. Cancer Res 42: 5458, 1982, Lijinsky W: Metabolism and cellular interactions of some aliphatic nitrogenous carcinogens. Biochem J 212: 599608, 1983, Farrelly JG, Thomas BJ, Lijinsky W: Metabolism and cellular interactions of N-nitrosodiethanolamine. Carcinogenesis 1: 157160. 112: 229239, 1986, Lijinsky W, Reuber MD: Carcinogenicity of deuteriumlabeled N-nitroso-N-methyleyclohexylamine in rats. Cancer Lett 8: 2934, 1979. Clipboard, Search History, and several other advanced features are temporarily unavailable.

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